Based on the 2004 SEGA arcade game of the same name, Ghost Squad is a rail shooter where the player fights as a part of an elite squad through multiple levels. Enemies that suddenly appear need to be shot, bombs have to be defused and hostages need to be rescued. The Wiimote controller is used as a light gun and the Wii Zapper is also supported. Each level presents a series of alternate routes for the player can select. Playing through the game there are new weapons and game modes to unlock, like Ninja Mode and Paradise Mode. There are 25 weapons (machine guns, submachine guns, pistols, sniper rifles, shotguns, crossbows, ...) 14 costumes and no less than 48 difficulty levels. Improvements over the arcade version include 4-player multiplayer in the two Party modes and support for online high scores.