In Bomberman Blast, the player can choose the trademark battle mode featured in Bomberman games, allowing up to eight players at a time, with online gameplay available; or a story mode, where the player’s Miis have been kidnapped, and it’s up to him to find them. This makes the player go on a journey through five different worlds, each with its own distinct boss, while also featuring tons of different enemies. In addition, there is also a "Bomberman for Beginners" mode that welcomes newcomers to the series with basic tutorials to teach the traditional Bomberman mechanics.
There are several new items relative to the Bomberman series, with some of them being activated through use of the Wii Remote’s shaking feature, introducing a new element in the series. Players can also buy upgrades and power-ups, as well as use their Miis during gameplay.
There is a WiiWare digital version that does not contain the story mode nor the beginner mode, as well as not allowing the player to purchase the extra items.